Epitalon
Epitalon Peptide (Epithalon or Epithalone) is a synthetic variation of Epithalamin, a peptide secreted in the pineal gland of the brain that is comprised of four amino acids. Epitalon increases the natural production of telomerase, an enzyme that helps cells make telomeres, the productive parts of our DNA. The production of telomeres helps the body to make new cells and rejuvenate the old ones. It is also responsible for the maintenance of stem cells, which serve as a repair system for the body. This helps slow the aging process at the cellular level!
The benefits of Epitalon peptide include:
- Increased telomeres, cell replication and rejuvenation, extending life expectancy
- Prevention of neurodegenerative diseases such as dementia
- DNA repair
- Oncostatic and antimetastatic properties (Suppresses tumor development and reduced number of metastases in mice that developed spontaneous tumors)
- Powerful antioxidant, protecting against oxidative stress
- Stimulates melatonin production
- Improves deep sleep and sleep/wake cycle
- Healthier neuroendocrine & immune system
- Accelerates wound healing
- Increases energy
- Improves skin health and appearance
To date, there are no known side effects for the use of Epitalon. This includes in clinical trials and those taking it on their own.
Dosing
10mg subcutaneous injection daily for 10 days. This is completed every 6 months.
Pricing
Contact for pricing.
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Epitalon Clinical Information
Mechanism
Epitalon is a 4-amino-acid synthetic peptide derived from a pineal-gland protein. Preclinical studies suggest it supports telomerase activity, melatonin/circadian regulation, and immune signaling.
Common Uses
- Longevity protocols
- Sleep and circadian rhythm support
- Adjunct in immune and cellular-aging plans
Dosing
Typically 5–10 mg subcutaneously daily for 10–20 days, 1–2 cycles per year (pulse-dose model from original Russian protocols).
Side Effects
Generally mild — injection-site reactions, occasional brief headache.
Contraindications
- Active malignancy (theoretical caution given telomerase activity)
- Pregnancy or breastfeeding
Medically reviewed by: Diana Medina, MMS, PA-C — Florida-licensed Physician Assistant
Medical Director: Luis Campillo, MD
Last reviewed: May 20, 2026
This page is for educational purposes only and does not constitute medical advice. All treatments require an individualized medical evaluation. DMHealth provides services via telehealth to Florida residents under the medical supervision of Luis Campillo, MD, in accordance with Florida Statutes § 458.347 governing physician assistant practice. Some statements have not been evaluated by the U.S. Food and Drug Administration; products mentioned are not intended to diagnose, treat, cure, or prevent any disease.