Testosterone Therapy
Testosterone therapy has been shown to have positive effects on muscle building. As testosterone levels increase, your androgen receptors are activated, increasing the rate of muscle growth. Higher T levels also increase a muscle-stimulating hormone called IGF-1, which activates growth hormone—which helps build your bones and muscles.
Testosterone replacement therapy (TRT) has been shown to have several potential benefits, including:
- Increased muscle mass and strength: Testosterone is an anabolic hormone that promotes the growth of muscle tissue, and TRT can help to increase muscle mass and strength in males with low levels.
- Improved sexual function: TRT has been shown to improve libido, erectile function, and overall sexual satisfaction.
- Increased bone density: TRT can help to reduce the risk of osteoporosis and other bone-related conditions in individuals with low levels.
- Improved mood and cognitive function: Testosterone has a positive impact on mood and cognitive function, and TRT has been shown to improve symptoms of depression, anxiety, and cognitive decline.
- Reduced risk of cardiovascular disease: Some studies have suggested that TRT may help to reduce the risk of cardiovascular disease in men with low levels.
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. All content on this website is for informational purposes only. The content is not intended to diagnose, treat, cure or prevent diseases.
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Testosterone Replacement Therapy (TRT) Clinical Information
How TRT Works
Testosterone Replacement Therapy supplements the body’s testosterone when its own production has fallen below normal range and is producing symptoms. TRT is most commonly delivered as a weekly or twice-weekly subcutaneous or intramuscular injection of testosterone cypionate or enanthate, with adjunctive medications (hCG, anastrozole, or enclomiphene) used when clinically indicated.
Indications
- Clinically diagnosed male hypogonadism (low testosterone confirmed by two morning blood draws plus symptoms)
- Persistent symptoms: fatigue, low libido, ED, depressed mood, brain fog, muscle loss, increased body fat, reduced bone density
Contraindications
- Active or untreated prostate cancer
- Active breast cancer
- Severe untreated sleep apnea
- Severe lower urinary tract symptoms (uncontrolled BPH)
- Hematocrit (red blood cell %) above 54% at baseline
- Recent heart attack, stroke, or unstable cardiovascular disease
- Pregnancy in any partner with whom transfer could occur (testosterone is teratogenic)
- Current desire for fertility (TRT suppresses sperm production; alternatives like enclomiphene or hCG may be preferable)
Required Baseline Workup
- Total and free testosterone — two morning draws on separate days
- LH, FSH, prolactin (to determine primary vs. secondary hypogonadism)
- Estradiol (sensitive assay)
- SHBG
- Complete blood count (hematocrit baseline)
- PSA (men age 40+)
- Lipid panel and HbA1c
- Thyroid panel
Monitoring on TRT
- Re-check testosterone, estradiol, hematocrit, PSA at 3 months, 6 months, then every 6–12 months
- Symptom-based dose adjustment in conjunction with labs
- Address erythrocytosis (high hematocrit) with dose reduction, hydration, or therapeutic phlebotomy if needed
Common Side Effects
- Acne or oily skin
- Fluid retention
- Mood changes (typically improvements; rarely irritability)
- Increased red blood cell count (hematocrit)
- Testicular size reduction (related to suppression of natural production)
- Worsening sleep apnea in susceptible men
- Breast tissue tenderness or gynecomastia (estradiol-related; managed if it occurs)
Important Clinical Considerations
- Cardiovascular safety: The TRAVERSE trial (NEJM 2023) showed TRT did not increase major adverse cardiovascular events in hypogonadal men with cardiovascular risk factors compared to placebo. Older blanket cardiovascular warnings have been moderated based on this evidence.
- Prostate cancer: Modern evidence does not support the historical concern that TRT causes prostate cancer in men without active disease. Men with a personal or strong family history should be screened thoroughly first.
- Fertility: External testosterone shuts down the body’s own production, which suppresses sperm production. Discuss fertility plans before starting.
How DMHealth Prescribes TRT
- Free virtual consultation to review symptoms and history
- Full baseline labs as outlined above (two morning testosterone draws required)
- Provider evaluation by Diana Medina, MMS, PA-C, under Luis Campillo, MD’s supervision
- Personalized protocol — injection vs. cream, frequency, adjunctive medications
- Prescription via verified compounding pharmacy
- Structured monitoring schedule with bloodwork at 3 and 6 months
Testosterone Therapy (TRT) in Weston, FL — Frequently Asked Questions
Common questions about testosterone replacement therapy (TRT) at DMHealth, our Weston clinic, and Florida telehealth.
What is testosterone replacement therapy (TRT)?
Testosterone replacement therapy (TRT) is a prescription treatment that supplements the body’s testosterone when its own production has fallen below the normal range and is causing symptoms. It is most commonly given as a weekly or twice-weekly injection of testosterone cypionate or enanthate, and at DMHealth it is prescribed only after a full medical evaluation by our provider.
What symptoms of low testosterone prompt an evaluation?
Symptoms that commonly prompt an evaluation include fatigue, low libido, erectile difficulties, depressed mood, difficulty concentrating, loss of muscle, increased body fat, and reduced bone density. These symptoms can have many causes, so DMHealth confirms low testosterone with lab work before any treatment decision is made.
How is low testosterone diagnosed at DMHealth?
Diagnosis starts with lab work: total and free testosterone measured on two separate morning blood draws, along with related labs such as LH, FSH, estradiol, a complete blood count, and PSA for men age 40 and older. Your provider reviews these results together with your symptoms to determine whether TRT is appropriate for you.
Do I need a prescription for testosterone therapy?
Yes. Testosterone is a prescription-only medication and a federally controlled substance, so it cannot be purchased over the counter. At DMHealth, TRT is prescribed by Diana Medina, MMS, PA-C, under the supervision of our Medical Director, Luis Campillo, MD, and only after your labs and evaluation support a diagnosis.
Who is not a candidate for testosterone therapy?
TRT is not appropriate for everyone, and candidacy is always determined by your provider after evaluation. Conditions such as active prostate or breast cancer, severe untreated sleep apnea, a high red blood cell count, or a recent heart attack or stroke can rule it out, and men who want to preserve fertility may be guided toward alternatives. Your provider reviews your full history before any prescription.
Where can I find TRT near me in Weston, FL?
DMHealth provides testosterone therapy in person at our Weston clinic at 2700 Glades Cir Ste 136, Weston, FL 33327, and by telehealth to patients anywhere in Florida. Call (904) 297-8234, Monday through Friday, 8am to 5pm, to schedule a visit either way.
What monitoring does TRT require?
After you start, DMHealth re-checks labs, including testosterone, estradiol, hematocrit, and PSA, at 3 months and 6 months, then every 6 to 12 months. Your provider adjusts your protocol based on these labs together with your symptoms, and ongoing follow-up is part of the program.
How much does testosterone therapy cost at DMHealth?
Pricing depends on your personalized protocol, which is reviewed during your consultation. Book a consultation to go over your symptoms, labs, and a plan for your situation.
Related services at DMHealth: Hormone optimization · Sexual wellness treatments · Peptide therapy
Medically reviewed by: Diana Medina, MMS, PA-C — Florida-licensed Physician Assistant
Medical Director: Luis Campillo, MD
Last reviewed: May 20, 2026
This page is for educational purposes only and does not constitute medical advice. All treatments require an individualized medical evaluation. DMHealth provides services via telehealth to Florida residents under the medical supervision of Luis Campillo, MD, in accordance with Florida Statutes § 458.347 governing physician assistant practice. Some statements have not been evaluated by the U.S. Food and Drug Administration; products mentioned are not intended to diagnose, treat, cure, or prevent any disease.