SERMORELIN
Sermorelin is a synthetic growth hormone–releasing hormone (GHRH) peptide composed of 29 amino acids that stimulates the pituitary gland to increase the body’s natural production of growth hormone. Unlike exogenous growth hormone.
Sermorelin works upstream to support physiologic growth hormone pulsatility, helping maintain normal hormonal regulation while supporting metabolic health and recovery.
Applications
- Supports lean muscle preservation and recovery
- Improves sleep quality and nighttime growth hormone release
- Enhances fat metabolism and body composition
- Supports skin, hair, and connective tissue health
- Aids recovery from physical stress and exercise
- Supports healthy aging and metabolic resilience
Dosing
200–300 mcg subcutaneously nightly on an empty stomach, 5 days per week
(Dosing may be adjusted based on individual response and clinical goals)
Pricing
Contact for pricing.
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Sermorelin Clinical Information
Mechanism
Sermorelin is a 29-amino-acid GHRH analog that stimulates the body’s own pituitary to release growth hormone. Short half-life (~10–20 minutes) preserves the natural pulsatile pattern.
Common Uses
- Gentle anti-aging and recovery support
- Sleep quality, especially deep sleep
- Body composition over 3–6 month cycles
Dosing
Typically 100–500 mcg subcutaneously at bedtime. Cycle 3–6 months on, then break.
Side Effects
- Injection-site reactions
- Brief flush
- Vivid dreams
Contraindications
- Active malignancy
- Pregnancy or breastfeeding
- Severe insulin resistance
Medically reviewed by: Diana Medina, MMS, PA-C — Florida-licensed Physician Assistant
Medical Director: Luis Campillo, MD
Last reviewed: May 20, 2026
This page is for educational purposes only and does not constitute medical advice. All treatments require an individualized medical evaluation. DMHealth provides services via telehealth to Florida residents under the medical supervision of Luis Campillo, MD, in accordance with Florida Statutes § 458.347 governing physician assistant practice. Some statements have not been evaluated by the U.S. Food and Drug Administration; products mentioned are not intended to diagnose, treat, cure, or prevent any disease.